منابع مشابه
Fetal lung maturity testing.
Hyaline membrane disease (HMD) is a disorder primarily affecting premature infants and is a significant cause of morbidity and mortality in this population. The disorder is characterized by widespread atelectasis and an inability of the neonate to expand his or her lungs. Secondary hemor rhage, edema and desquamation of alveolar lining cells then occur which further compromise respira tory func...
متن کاملProspective clinical evaluation of an improved fluorescence polarization assay for predicting fetal lung maturity.
We performed a prospective clinical evaluation of our newly developed fluorescence polarization procedure to predict fetal lung maturity (Clin Chem 1986;32:248-54). Net fluorescence polarization was measured at 34 degrees C after a 6.5-min incubation of amniotic fluid with fluorophore. For the 26 cases of neonatal respiratory distress syndrome encountered in 196 deliveries, the net polarization...
متن کاملBiochemical assessment of fetal lung maturity.
The relationship between the enzyme phosphatidate phosphohydrolase (PAPase) and lecithin/sphingomyelin (L/S) ratio in amniotic fluid was evaluated in normal human pregnancies and in several pregnancies complicated by Rh isoimmunization. An increase in PAPase activity in amniotic fluid appears to parallel the increase in L/S ratio after 33 weeks gestation in normal subjects. These data suggest t...
متن کاملRoutine diagnosis of fetal lung maturity.
The respiratory distress syndrome (RDS) is the most frequent postnatal complication of prematurity having a 25% lethal outcome even today (KEUTH [6]). The same author reports that RDS affects 8% of an unselected population of premature infants and 20% of a negatively selected population found in clinical departments for premature babies. Hence avoidance of prematurity is one of the most importa...
متن کاملMulticenter evaluation of TDx test for assessing fetal lung maturity.
"TDx Fetal Lung Maturity," an automated assay that measures the relative concentrations of surfactant and albumin in amniotic fluid, was compared with the lecithin/sphingomyelin (L/S) ratio and phosphatidylglycerol determination at five clinical sites. A total of 695 amniotic fluid samples were analyzed, of which 312 were followed by delivery of the infant within three days of sample collection...
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ژورنال
عنوان ژورنال: BMJ
سال: 1971
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5779.116-b